[Sar1, Ile8]-Angiotensin II - Ontores  

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[Sar1, Ile8]-Angiotensin II

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名称 [Sar1, Ile8]-Angiotensin II
CAS No. 67724-27-0
目录号 ONP10022
规格 mg/g
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 968.15
序列结构 H-SAR-ARG-VAL-TYR-ILE-HIS-PRO-ILE-OH
库存
产品简述 The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1, Ile8] derivative of angiotensin II. However, this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells, and never reduced aldosterone production to basal levels.